Postbaccalaureate Fellow

National Institutes of Health, Bethesda, MD | Aug 2014 – June 2015 (1 year)

Screenshot of miRDeep2 output showing a predicted microRNA in Hydractinia that passed filtering based on secondary structure, miRDeep2 score, and strand homogeneity. — High-confidence microRNA candidate in Hydractinia. This screenshot shows miRDeep2 output for a predicted microRNA that passed automated filtering based on secondary structure and computational scoring. (Schnitzler et al 2022).

Screenshot of miRDeep2 output showing a predicted microRNA in Hydractinia that passed filtering based on secondary structure, miRDeep2 score, and strand homogeneity. — High-confidence microRNA candidate in Hydractinia. This screenshot shows miRDeep2 output for a predicted microRNA that passed automated filtering based on secondary structure and computational scoring. (Schnitzler et al 2022).

Summary

Collaborated with computational biologists to analyze the genomes of Hydractinia echinata and Hydractinia symbiolongicarpus by designing and implementing analysis of novel small RNAs during head regeneration for publication
Employed a domain architecture search strategy to identify TRAF immune genes in the genomes of multiple eukaryotes to explore Cnidarian evolution

Presentations

Klasfeld, S., Baxevanis, A., & Schnitzler, C. (2015, October 22). Small RNA discovery and expression during regeneration in the colonial hydroid, Hydractinia [PowerPoint slides]. Bioinformatics Scientific Interest Group (BSIG), NIH.

Selected Awards

Outstanding Poster Award at NIH Post Baccalaureate Poster Day 2015
Bioinformatics-Scientific Interest Group 3rd Annual Poster Day Winner (First Place)

Publications

The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals

Schnitzler, C., ..., Klasfeld, S., ..., & Baxevanis, A.

Genome Res. • 2024

Presentations

Small RNA discovery and expression during regeneration in the colonial hydroid, Hydractinia

Klasfeld, S., Baxevanis, A., & Schnitzler, C.

PowerPoint slides Bioinformatics Scientific Interest Group (BSIG), NIH • October 22, 2015

References

The Hydractinia genome project portal NIH Bioinformatics Scientific Interest Group NIH Postbaccalaureate Poster Day Hydractinia Genome Project Portal Baxevanis Lab Schnitzler Lab miRBase mirDeep2

More Work Experiences

Graduate Student Researcher

University of Pennsylvania, Philadelphia, PA | Aug 2015 – Feb 2022 (6 years)

Summer Undergraduate Researcher

J. Craig Venter Institute, Rockville, MD | June 2013 – August 2013 (3 months)